A high-coverage Neandertal genome from Vindija Cave in Croatia
13 Pages · 2017 · 1.06 MB · English
12, e1006340. (2016). doi:10.1371/journal.pgen.1006340 Medline. 6. S. Sankararaman, S. Mallick, M. Dannemann, K. Prüfer, J. Kelso, S. Pääbo, N Primer extension capture: Targeted sequence retrieval from heavily degraded. DNA sources. J. Vis. Exp. 3 1573 (2009). Medline on October 6, 2017.
Whole-genome comparison of two Acinetobacter baumannii isolates from a single patient, where ...
5 Pages · 2011 · 167 KB · English
The first, AB210, was recovered before tigecycline therapy and was Published by Oxford University Press on behalf of the British Society for Clinical isolates AB210 and AB211 have been described previously.3 As. OXA-23 interpreted according to BSAC guidelines.9 Genomic DNA was extracted.
Rat genome variation and complex traits
144 Pages · 2014 · 7.7 MB · English
(met een samenvatting in het Nederlands). Proefschrift ter verkrijging van de graad van doctor aan de Universiteit Utrecht op gezag van de rector could possibly restore the open reading frame by investigating the high of low diversity are small (median 400kb), with no blocks over 35 Mb.
Parallel evolution of transcriptome architecture during genome reorganization
14 Pages · 2011 · 2.04 MB · English
terized how microbes deal with operon instability by mapping and comparing transcriptome architectures of four mutations on changes in gene expression (Wray 2007; Stern and. Orgogozo .. (crRNA) and RAMP module Cas proteins (Cmr) form a ribonu- .. straints (physiological and environmen-.
Bacteriophage Mu Genome Sequence: Analysis and Comparison with Mu
23 Pages · 2002 · 2.1 MB · English
prophage that is thought to be responsible for the virulence of the D. nodosus strains that cause ovine footrot.90(Seebelowforgp30’sprobablefunction
An ultra-low-input native ChIP-seq protocol for genome-wide profiling of rare cell populations
8 Pages · 2015 · 2.07 MB · English
Combined chromatin immunoprecipitation and next-generation sequencing (ChIP-seq) has enabled genome-wide epigenetic profiling of numerous cell lines and tissue types. A major limitation of ChIP-seq, however, is the large number of cells required to generate high-quality data sets, precluding the
Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide ...
7 Pages · 2012 · 367 KB · English
Disorders that share genetic risk factors often are placed in closely related diagnostic categories and treated similarly. genetic and functional studies. disorder A or B as. KDA ¼ KTA DA+KTB DA and KDB ¼ KTB DB+KTA DB. The diagnosis misclassification rate, the proportion of those diagnosed as.
Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR&ast
9 Pages · 2012 · 1.36 MB · English
(GWAS) to identify genetic variation influencing susceptibility to citalopram-induced side effects. The analysis sample consisted . This was carried out to confirm that the factor solution was robust across treatment . observed, given the null hypothesis, and of the probability of obtaining a test
Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion
6 Pages · 2017 · 1.23 MB · English
Single-cell genomics is important for biology and medicine. However, current whole-genome amplification (WGA) methods are limited by low accuracy of copy-number variation (CNV) detection and low amplification fidelity. Here we report an improved single-cell WGA method,. Linear Amplification via
The Role of Plastome-Genome Incompatibility and Biparental Plastid
8 Pages · 2007 · 1.27 MB · English
Zantedeschia aethiopica Cultivars (section Aestivae) 59 41 171 + Yao et al. 1994 Zantedeschia 3 spp. Z. 5 spp. 10-98 3-90 1-6 1307 + This study 1
Whole-genome sequencing reveals transmission of Staphylococcus aureus from humans to green ...
27 Pages · 2016 · 2.24 MB · English
Running title: Human to monkeys Staphylococcus aureus transmission. 32 panton-valentine leukocidin is a very potent cytotoxic factor for human.
Genome Biol. Evol. 6: 2851-2865
15 Pages · 2014 · 640 KB · English
Hsp90 is one of the most abundant and conserved proteins in the cell. Reduced levels or activity of Hsp90 causes defects in many cellular processes and also reveals genetic and nongenetic variation within a population. Despite information about Hsp90 protein– protein interactions, a global view o
Human Y-chromosome variation in the genome-sequencing era
13 Pages · 2017 · 722 KB · English
recombination, which leads to a high degree of structural variation2–4. genetic variation becoming a key part of studies of human evolution, population history, genealogy, forensics and male a rise of 'citizen scientists', whose interest in resequencing their own Y chromosomes is generating a w
Genome Sequence of Additional Caenorhabditis species: Enhancing
13 Pages · 2003 · 381 KB · English
Additional Caenorhabditis Genomes 1 Genome Sequence of Additional Caenorhabditis species: Enhancing the Utility of C. elegans as a Model Organism
Functional Annotation of the Ophiostoma novo-ulmi Genome
55 Pages · 2014 · 2.07 MB · English
glycoprotein; RE, repetitive element; RIP, repeat-induced point mutation; ST, they allow the fungus to breach elm structural barriers (bark) and gain access to . Non-coding RNAs (ncRNA), repeat elements and analysis of RIP (possibly StcA) – ST and aflatoxin are both polyketide-derived products,