Prevalence of diabetes in Brazil over time: a systematic review with meta-analysis

Prevalence of diabetes in Brazil over time: a systematic review with meta-analysis

13 Pages · 2016 · 1.34 MB · English

The biggest increase was detected in studies using complex diagnosis: 7.4 % (95 % CI 7.1–7.7) in the 1980s to 15.7 % (95 % CI 9.8–24.3) in the 2010s. In conclusion, despite high heterogeneity, this study observed a high prevalence of diabetes in Brazilian adults over time and with a progressive

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Telo et al Diabetol Metab Syndr (2016) 8:65 DOI 101186/s1309801601811 REVIEW Prevalence of diabetes in Brazil over time: a systematic review with meta analysis Gabriela H Telo 1*, Felipe Vogt Cureau 2, Martina S de Souza 1, Thais S Andrade 1, Fabiana Copês 1,3 and Beatriz D Schaan 1,2,4 Abstract Diabetes is one of the most important epidemic diseases of this century and the number of people with diabetes has more than doubled over the past three decades Our aim was to estimate the prevalence of diabetes in the adult Brazilian population and analyze the trends for the last three decades through a systematic review with metaanalysis This review included observational studies published between 1980 and 2015, which were independently identi fied by two reviewers in five databases Random effect models were used to estimate the prevalence and trends of diabetes In total, 50 articles were included in this review Three different patterns for diabetes diagnosis were identi fied: selfreport (36 studies), fasting glucose (7 studies), and complex diagnosis (fasting glucose, oral glucose tolerance test, and selfreport; 7 studies) The prevalence of diabetes was 56 % (95 % CI 50–63; I 2 = 100 %) by selfreport, 66 % (95 % CI 48–89; I 2 = 94 %) by fasting glucose, and 119 % (95 % CI 77–178 I 2 = 100 %) by complex diagnosis In trend analyses, we observed an increase in the prevalence of diabetes over time The biggest increase was detected in stud ies using complex diagnosis: 74 % (95 % CI 71–77) in the 1980s to 157 % (95 % CI 98–243) in the 2010s In conclu sion, despite high heterogeneity, this study observed a high prevalence of diabetes in Brazilian adults over time and with a progressive increase in the last 35 years Keywords: Type 2 diabetes, Prevalence, Brazil © 2016 The Author(s) This article is distributed under the terms of the Creative Commons Attribution 40 International License (http://creativecommonsorg/licenses/by/40/ ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made The Creative Commons Public Domain Dedication waiver ( http://creativecommonsorg/ publicdomain/zero/10/ ) applies to the data made available in this article, unless otherwise stated Background Diabetes is one of the most important epidemic diseases of this century The global prevalence of type 2 diabetes is increasing worldwide as a result of population ageing [ 1], rising rates of overweight and obesity in adults as well as youth [ 2], and reduced risk of mortality among patients with diabetes [ 3] The number of people with diabetes has more than doubled over the past three decades in nearly every nation of the world [ 4] In 2014, the global preva lence of diabetes was estimated to be 9  % among adults older than 18  years old [ 5] It has been projected that there will be 366 million adults with diabetes in 2030 [ 6] and, despite recent declines in mortality, diabetes will be the seventh leading cause of death in 15 years [ 7], making it one of the most important public health challenges to all nations [ 8] The major burden of diabetes is now taking place in developing rather than in developed countries, and 80  % of patients with diabetes live in less developed areas [ 8] All the Latin American countries have undergone rapid demographic, epidemiological and nutritional transi tions [ 9], which strongly contributed to the increasing prevalence of diabetes Brazil is one of the most impor tant examples of this alarming problem in less developed societies with the fourth largest number of people with type 2 diabetes [ 10] In the South and Central America region, 80–113 % of the adult population have diabetes Of these,

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