Hydrodynamic Considerations in Bioreactor Selection and Design

Hydrodynamic Considerations in Bioreactor Selection and Design

12 Pages · 2015 · 6.03 MB · English

developments and the fluid mechanic issues that should to be and may cause concentrations of a toxic substance to build up .. TUBE SEPARATING THE RISER AND DOWN COMER, AND (C) A SECTIONED DRAUGHT TUBE.

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M ech anical E ngine erin g C onfe re nc e P re se n ta tion s, P ape rs, a nd P roc eed in gs M ech anical E ngine erin g 82010 H ydr od yn amic C onside ra tions in B ioreac tor S elec tion a nd D esign E nes K adic I o w a S ta te U niv er sit y Theo dore J H eindel I o w a S ta te U niv er sit y , theinde [email protected] te e du F ollo w thi s and a ddition al w orks at: h tt ps://l ib dr ias ta te e du/me_c onf P art of the Ac ous tic s, D yn amic s, and C ontrols C ommon s , B ioche mical a nd Biomo lecul ar E ngine erin g C ommon s , a nd the C omput erA ide d E ngine erin g a nd D esi gn C ommon s Thi s Confe re nc e P roc eed in g i s br ought to y ou for f re e a nd ope n acce ss b y the M ech anical E ngine erin g a t Iow a S ta te U niversit y Di git al R eposit ory I t h as be en a cce pt ed for inclusion in M ech anical E ngine erin g C onfe re nc e P re se n ta tion s, P ape rs, a nd P roc eed in gs b y an a uthor iz e d a dmini str ator of I ow a S ta te U niversit y Di git al R eposit ory F or mor e information, p leas e c onta ct d ig ir [email protected] asta te e du R ecomme nded Citation K ad ic, E nes a nd H einde l, The odore J, " Hydr ody namic C onside ra tion s in B ioreact or S ele ct ion a nd D esi gn " (2010) M ech an ic al E ngin eer in g Co nferen ce P re sen ta tio ns, P ap er s, a nd P ro ce ed in gs 120 h tt ps://l ib dr ias ta te e du/me_c onf/120 H ydr od yn amic C onside ra tions in B ioreac tor S election a nd D esign A bs tract The b iological pr oduction of r ene wab le f uels a nd che micals, medic ine s, and pr otein s is not pos sible w ithout a pr ope rly f unct ionin g bioreact or B ior eact or s a re ex pected t o me et s ev eral b asic r equir eme nts a nd cr eate c ond ition s favor ab le t o the b iological m ate rial s uch th at the de sired pr oduct ion is maximi ze d The b asic r e quir eme nts, w hich a re s tron gly influe nced b y fluid me chanic pr inciples, m ay include minim um dam ag e t o the b iological m ate rial , m axim um r eact or v olume ut ili za tion, opt imize d g asliquid m ass tr an sfe r, a nd/or e nh anc ed m ass tr an sfe r from the l iquid to the b iological spe cie s Ea ch of the se g oal s m ay be a chieved w ithin a n y of the m ajor b ioreact or de sign s, w hich g ene ral

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